Cocaine Vaccine

Researchers at Baylor University are working to develop a vaccine for cocaine addiction:

The vaccine, currently in clinical trials, stimulates the immune system to attack the real thing when it's taken.

The immune system — unable to recognize cocaine and other drug molecules because they are so small — can't make antibodies to attack them.

To help the immune system distinguish the drug, Kosten attached inactivated cocaine to the outside of inactivated cholera proteins.

In response, the immune system not only makes antibodies to the combination, which is harmless, but also recognizes the potent naked drug when it's ingested. The antibodies bind to the cocaine and prevent it from reaching the brain, where it normally would generate the highs that are so addictive.